Trichuriasis is a soil-transmitted roundworm infection caused by Trichuris trichiura. It is a neglected tropical disease that affects hundreds of millions of people worldwide.
Trichuris trichiura infects humans in tropical or subtropical areas where there is poor sanitation and faecal contamination of the soil. Children are particularly affected. Treatment with mebendazole, albendazole or ivermectin prevents infections and reduces the risk of relapse.
what is trichuriasis?
Trichuriasis is an infection of the large intestine caused by a parasitic worm called Trichuris trichiura. This worm buries its threadlike anterior half into the lining of the bowel to feed on tissue secretions.
It is a common intestinal helminthic disease worldwide and affects over one-quarter of the world’s population. It is particularly prevalent in tropical Asia and less commonly in Africa and South America.
Humans can become infected if they swallow soil contaminated with whipworm eggs. Children are the most vulnerable group to trichuriasis.
Infection with Trichuris trichiura leads to a chronic inflammatory response of the gut and gastrointestinal tract, as well as blood loss due to oozing and bleeding at mucosal entry sites. It can cause severe anemia.
What are the symptoms of trichuriasis?
The symptoms of trichuriasis vary depending on the level of infection. Light infections can be asymptomatic, while moderate to severe infections may cause abdominal pain, painful diarrhoea, or bloody stool.
Infections that involve a high worm burden, such as those in children, can be accompanied by tenesmus and iron deficiency anemia. In severe cases, children may suffer from trichuris dysentery syndrome (TDS), which involves diarrhea and growth retardation.
What is the diagnosis of trichuriasis?
Diagnosis of trichuriasis relies on examination of stools for parasite eggs. This is done using microscopy and direct observation of saline smears.
Light infection is usually asymptomatic but patients can be depressed and experience abdominal pain, nocturia, recurrent diarrhea, and vomiting. In severe diseases worms may be found in the intestine, invading the bowel wall and causing inflammation.
In severe infections, a person can become anemic and have low blood counts. Ivermectin and mebendazole are effective treatments of trichuriasis. They should be used with caution during pregnancy because of the risk to the fetus.
Trichuriasis is a serious and chronic disease. It can lead to reduced quality of life, decreased educational performance, and reduced economic potential. Treatment is essential to improve the quality of life of those affected by trichuriasis.
Does ivermectin prevent trichuriasis?
Ivermectin is an antiparasitic drug that helps prevent a wide range of parasitic diseases. It is used to treat worms that cause infections in humans and animals, such as river blindness (onchocerciasis), intestinal infection from threadworms (strongyloidiasis) and mansonelliasis (Loa loa disease).
Ivermectin works by blocking the nerve and muscle functions of worms. This prevents worms from working properly and causes them to die. It is available in different strengths and is given as a tablet.
It can be taken alone or in combination with other medications. It is usually taken with a full glass of water on an empty stomach.
The recommended dosage is 150 mcg/kg of body weight taken as a single dose. It is usually taken for 10-12 days.
If you have trouble taking this medicine, talk to your doctor. He or she may be able to give you a prescription that is refillable.
It is important to tell your doctor about any other medications you are taking, including vitamins or supplements. These could increase your risk for serious side effects, such as high blood pressure or seizures.
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Ivermectin is a prescribed medication used to treat certain parasitic roundworm infections. It is available in the form of tablets and should be taken according to the directions of your doctor.
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Risk Factors of trichuriasis
Trichuriasis is one of 3 soil-transmitted helminth infections (STHs) that affect humans and is associated with poor sanitation. It is also the most common infection among children living in areas of extreme poverty.
Trichuriasis can impact the quality of life by causing tenesmus, diarrhea, iron deficiency anemia, and poor growth in children and adults. These problems often lead to cognitive delay and can have serious effects on the educational achievement of children.
The risk of trichuriasis can vary greatly from individual to individual. For example, a child’s immune system and genetics may play a role in their susceptibility to trichuriasis.
Some of these factors can be changed by treatment, but they can’t be completely removed. Therefore, it’s important to discuss your health with a healthcare provider and decide how to treat your condition.
Precautions
- The precautions to take when trichuriasis is suspected include drinking only clean water, eating food that has been thoroughly cleaned and washing hands after working with soil or playing in a sandbox.
- Children should also be vaccinated against the parasite before going to school.
- Trichuris trichiura is one of the three major soil-transmitted helminths (STHs). This cosmopolitan metazoan parasite is found in most developing countries and parts of Africa.
- When infected, the worms live in the intestine and cause disease. Symptoms of trichuriasis can include epigastric pain, diarrhoea, vomiting, weight loss, biliary ascariasis and rectal prolapse.
- Unlike ascariasis, the worms cannot be transmitted from one person to another, but a child could still become infected through contact with contaminated soil. The worms can be ingested through unwashed fruit or vegetables or soil-contaminated water from a sandbox.